[...] * Global epidemic and mobility model (GLEAM): big data and high performance computing model combining real-world data on populations and human mobility with elaborate stochastic models of disease transmission to model the spread of an influenza-like disease around the globe, in order to be able to test intervention strategies that could minimize the impact of potentially devastating epidemics. An interesting application case quantification of the risk of local Zika virus transmission in the continental US during the 2015-2016 ZIKV epidemic.